BDBM50071696 (S)-1-[((2S,3S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-2-oxo-3-phenylmethanesulfonylamino-piperidine-3-carboxylic acid ethyl ester::CHEMBL421136

SMILES CCOC(=O)[C@@]1(CCCN(CC(=O)N[C@H]2CCCN([C@H]2O)C(N)=N)C1=O)NS(=O)(=O)Cc1ccccc1

InChI Key InChIKey=YLPFNSPUPARBLY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50071696   

TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50071696((S)-1-[((2S,3S)-1-Carbamimidoyl-2-hydroxy-piperidi...)
Affinity DataIC50: 43nMAssay Description:In vitro inhibitory activity was evaluated against thrombin factor Xa (FXa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50071696((S)-1-[((2S,3S)-1-Carbamimidoyl-2-hydroxy-piperidi...)
Affinity DataIC50: 64nMAssay Description:In vitro inhibitory activity was evaluated against thrombin (FIIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50071696((S)-1-[((2S,3S)-1-Carbamimidoyl-2-hydroxy-piperidi...)
Affinity DataIC50: 202nMAssay Description:In vitro inhibitory activity was evaluated against human trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50071696((S)-1-[((2S,3S)-1-Carbamimidoyl-2-hydroxy-piperidi...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity was evaluated against thrombolytic enzyme plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed