BDBM50071456 CHEMBL3410246

SMILES CSc1cccc(NC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)c1

InChI Key InChIKey=UNCZUEUPSJKHGB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071456   

TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071456(CHEMBL3410246)
Affinity DataIC50: 360nMAssay Description:Inhibition of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071456(CHEMBL3410246)
Affinity DataIC50: 70nMAssay Description:Inhibition of purified human Pank1beta using d-[1-14C]pantothenate as substrate after 10 mins by radiochemical enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 2, mitochondrial(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071456(CHEMBL3410246)
Affinity DataIC50: 92nMAssay Description:Inhibition of purified human Pank2 using d-[1-14C]pantothenate as substrate after 10 mins by radiochemical enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071456(CHEMBL3410246)
Affinity DataIC50: 25nMAssay Description:Inhibition of purified human Pank3 using d-[1-14C]pantothenate as substrate after 10 mins by radiochemical enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50071456(CHEMBL3410246)
Affinity DataIC50: 140nMAssay Description:Inhibition of Pank1beta (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed