BDBM50071279 3,4-Dichloro-N-(4-{2-[(S)-2-hydroxy-3-(pyridin-3-yloxy)-propylamino]-ethyl}-phenyl)-benzenesulfonamide::CHEMBL65042

SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)cc1)COc1cccnc1

InChI Key InChIKey=SWFWBELGCQKLLB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50071279   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071279(3,4-Dichloro-N-(4-{2-[(S)-2-hydroxy-3-(pyridin-3-y...)
Affinity DataIC50: 360nMAssay Description:Evaluated for its agonist activity and the binding affinity against human Beta-2 adrenergic receptor in membranes from chinese hamster ovary cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071279(3,4-Dichloro-N-(4-{2-[(S)-2-hydroxy-3-(pyridin-3-y...)
Affinity DataIC50: 290nMAssay Description:Evaluated for its agonist activity and the binding affinity against human Beta-1 adrenergic receptor in membranes from chinese hamster ovary cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071279(3,4-Dichloro-N-(4-{2-[(S)-2-hydroxy-3-(pyridin-3-y...)
Affinity DataEC50:  24nMAssay Description:Evaluated for Adenylyl cyclase activation as % of the maximal stimulation with isoproterenol at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed