BDBM50071278 CHEMBL304878::N-(4-{2-[(S)-3-(4-Fluoro-phenoxy)-2-hydroxy-propylamino]-ethyl}-phenyl)-4-iodo-benzenesulfonamide

SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(I)cc2)cc1)COc1ccc(F)cc1

InChI Key InChIKey=QLHQVTPMIQWMSN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50071278   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071278(N-(4-{2-[(S)-3-(4-Fluoro-phenoxy)-2-hydroxy-propyl...)
Affinity DataIC50: 100nMAssay Description:Evaluated for its agonist activity and the binding affinity against human Beta-2 adrenergic receptor in membranes from chinese hamster ovary cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071278(N-(4-{2-[(S)-3-(4-Fluoro-phenoxy)-2-hydroxy-propyl...)
Affinity DataEC50:  18nMAssay Description:Evaluated for its agonist activity against human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071278(N-(4-{2-[(S)-3-(4-Fluoro-phenoxy)-2-hydroxy-propyl...)
Affinity DataIC50: 910nMAssay Description:Evaluated for its agonist activity and the binding affinity against human Beta-1 adrenergic receptor in membranes from chinese hamster ovary cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed