BDBM50071220 2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine::CHEMBL64671

SMILES COc1cccc(c1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1

InChI Key InChIKey=SBXMILAGIXPXOK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50071220   

TargetD(2) dopamine receptor(Human)
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071220(2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Affinity DataIC50: 490nMAssay Description:Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071220(2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Affinity DataIC50: 700nMAssay Description:Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071220(2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Affinity DataIC50: 17nMAssay Description:Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071220(2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed