BDBM50071204 4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl::CHEMBL60957

SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2cnccn2)c1

InChI Key InChIKey=WVEQYQHSBOYABA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50071204   

TargetD(4) dopamine receptor(Human)
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071204(4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-3,4,5,6...)
Affinity DataIC50: 25nMAssay Description:Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071204(4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-3,4,5,6...)
Affinity DataIC50: 400nMAssay Description:Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071204(4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-3,4,5,6...)
Affinity DataIC50: 480nMAssay Description:Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071204(4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-3,4,5,6...)
Affinity DataIC50: 450nMAssay Description:Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed