BDBM50071152 (2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarboxylic acid::CHEMBL292553

SMILES N[C@@]1(C[C@@H](N(CCc2ccccc2)C1)C(O)=O)C(O)=O

InChI Key InChIKey=IMJOFZFQWDCAMA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071152   

TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071152((2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarb...)
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071152((2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarb...)
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071152((2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarb...)
Affinity DataIC50: 1.66E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071152((2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarb...)
Affinity DataIC50: 6.10E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071152((2R,4R)-4-Amino-1-phenethyl-pyrrolidine-2,4-dicarb...)
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 4 expressed in RGT cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed