BDBM50070707 (S)-5-Guanidino-2-(toluene-4-sulfonylamino)-pentanoic acid methyl ester::CHEMBL44752

SMILES COC(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=FKMJXALNHKIDOD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50070707   

TargetProthrombin(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50070707((S)-5-Guanidino-2-(toluene-4-sulfonylamino)-pentan...)
Affinity DataIC50: 8.90E+4nMpH: 8.3Assay Description:Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50070707((S)-5-Guanidino-2-(toluene-4-sulfonylamino)-pentan...)
Affinity DataIC50: 1.00E+6nMAssay Description:Concentration at which the clotting time was prolonged by twice the control was determined using topical bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed