BDBM50070565 5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL39016

SMILES CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(NC)nc1OC

InChI Key InChIKey=UXEPXLWCTJUUTO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50070565   

TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070565(5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2...)
Affinity DataIC50: 43nMAssay Description:Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070565(5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2...)
Affinity DataIC50: 43nMAssay Description:Concentration of compound required to inhibit the binding of radioligand [3H]spiperone to Dopamine receptor D2 in rat brain synaptic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070565(5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2...)
Affinity DataIC50: 1.26nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070565(5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed