BDBM50070510 3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-2-methyl-2,3-dihydro-isoindol-1-one::CHEMBL35114

SMILES COc1ccc(cc1)N1CCN(CCC2N(C)C(=O)c3ccccc23)CC1

InChI Key InChIKey=JSGIEHICMIFPBV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50070510   

TargetD(4) dopamine receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50070510(3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  333nMAssay Description:In vitro binding affinity at human dopamine D4 receptor expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50070510(3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50070510(3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed