BDBM50070461 (2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-phenylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-2-methyl-succinamide::CHEMBL32285

SMILES CC(C)C[C@@H](C(=O)N[C@H](C(=O)Nc1ccccc1)C(C)(C)C)[C@](C)(CC=C)C(=O)NO

InChI Key InChIKey=RMDCZACTUKUROI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50070461   

TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070461((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-phenylcar...)
Affinity DataIC50: 95nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070461((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-phenylcar...)
Affinity DataIC50: 50nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070461((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-phenylcar...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed