BDBM50070449 2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-carboxylic acid ((S)-2-hydroxy-1-phenyl-ethyl)-amide::CHEMBL36353

SMILES OC[C@@H](NC(=O)N1C(CC1=O)SCc1ccccn1)c1ccccc1

InChI Key InChIKey=IRZVPGLYRJGEBO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070449   

TargetCapsid scaffolding protein(HHV-5)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070449(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibitory activity against human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070449(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory activity against porcine pancreatic elastase(PPE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070449(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory activity against human leukocyte elastase protease(HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070449(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070449(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed