BDBM50070359 1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperidin-3-yl]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::CHEMBL440465

SMILES Clc1ccc(cc1Cl)C1(CCCN2CCC(CC2)n2c3ccccc3[nH]c2=O)CCCN(C1)C(=O)c1ccccc1

InChI Key InChIKey=ODPRNYGWGVRXIG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50070359   

TargetNeuromedin-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070359(1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperid...)
Affinity DataIC50: 7.90nMAssay Description:Compound was evaluated for its ability to displace [3H]NKB binding in hNK3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070359(1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperid...)
Affinity DataIC50: 379nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070359(1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperid...)
Affinity DataIC50: 348nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50070359(1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperid...)
Affinity DataIC50: 1.58E+3nMAssay Description:Displacement of [125I]MIP-1beta from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed