BDBM50070128 CHEMBL12769::Quinoline-3-sulfonic acid (4-{2-[(S)-2-hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenyl)-amide

SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2cnc3ccccc3c2)cc1)COc1ccc(O)cc1

InChI Key InChIKey=WQRHGJVXZGJYHH-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070128   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070128(Quinoline-3-sulfonic acid (4-{2-[(S)-2-hydroxy-3-(...)
Affinity DataIC50: 240nMAssay Description:Binding affinity against cloned human beta-2 adrenergic receptor from CHO cells using [125I]iodocyanopindolol as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070128(Quinoline-3-sulfonic acid (4-{2-[(S)-2-hydroxy-3-(...)
Affinity DataEC50:  1.30nMAssay Description:Evaluated for its agonist activity against human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070128(Quinoline-3-sulfonic acid (4-{2-[(S)-2-hydroxy-3-(...)
Affinity DataIC50: 500nMAssay Description:Tested for binding affinity against cloned human beta-1 adrenergic receptor from CHO cells using [125I]iodocyanopindolol as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070128(Quinoline-3-sulfonic acid (4-{2-[(S)-2-hydroxy-3-(...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity against cloned human beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070128(Quinoline-3-sulfonic acid (4-{2-[(S)-2-hydroxy-3-(...)
Affinity DataEC50:  300nMAssay Description:Compound was tested for agonist activity against cloned human beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed