BDBM50070049 (4aR,10bR)-4,10b-Dimethyl-8-((Z)-styryl)-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one::CHEMBL129017

SMILES CN1[C@@H]2CCc3cc(\C=C/c4ccccc4)ccc3[C@@]2(C)CCC1=O

InChI Key InChIKey=YLMDSHIOZFJIOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50070049   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50070049((4aR,10bR)-4,10b-Dimethyl-8-((Z)-styryl)-1,4,4a,5,...)
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase type I enzyme based on the conversion of [3H]-T to [3H]DHT in nuclear membrane preparations fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50070049((4aR,10bR)-4,10b-Dimethyl-8-((Z)-styryl)-1,4,4a,5,...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase type 2 as [3H]T to [3H]-DHT conversion human prostate nuclear membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed