BDBM50069912 CHEMBL323118::N-[5-(2-Benzylamino-ethoxy)-2-fluoro-phenyl]-methanesulfonamide

SMILES CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1F

InChI Key InChIKey=HEHPXIHFYMLODY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069912   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069912(N-[5-(2-Benzylamino-ethoxy)-2-fluoro-phenyl]-metha...)
Affinity DataKi:  7.90nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069912(N-[5-(2-Benzylamino-ethoxy)-2-fluoro-phenyl]-metha...)
Affinity DataKi:  24nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069912(N-[5-(2-Benzylamino-ethoxy)-2-fluoro-phenyl]-metha...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity towards human cloned dopamine (hD3) receptor expressed in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069912(N-[5-(2-Benzylamino-ethoxy)-2-fluoro-phenyl]-metha...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards human cloned dopamine (hD2s) receptors expressed in CHO cell membranes using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed