BDBM50069910 4-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL103900

SMILES Oc1ccc(cc1)N1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=MKDLAVWJHBTGFQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069910   

TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069910(4-(4-Benzyl-piperazin-1-yl)-phenol | CHEMBL103900)
Affinity DataKi:  92nMAssay Description:Binding affinity towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069910(4-(4-Benzyl-piperazin-1-yl)-phenol | CHEMBL103900)
Affinity DataKi:  120nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069910(4-(4-Benzyl-piperazin-1-yl)-phenol | CHEMBL103900)
Affinity DataKi: >300nMAssay Description:Binding affinity towards human cloned dopamine (hD2s) receptors expressed in CHO cell membranes using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069910(4-(4-Benzyl-piperazin-1-yl)-phenol | CHEMBL103900)
Affinity DataKi: >400nMAssay Description:Binding affinity towards human cloned dopamine (hD3) receptor expressed in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed