BDBM50069650 5-({[(S)-2-(3-tert-Butyl-5-methyl-benzyloxy)-1-phenyl-ethyl]-methyl-amino}-methyl)-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL153310

SMILES CN(Cc1n[nH]c(=O)[nH]1)[C@H](COCc1cc(C)cc(c1)C(C)(C)C)c1ccccc1

InChI Key InChIKey=VCYXADWZHUWUAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069650   

TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069650(5-({[(S)-2-(3-tert-Butyl-5-methyl-benzyloxy)-1-phe...)
Affinity DataIC50: 0.420nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed