BDBM50069648 (S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethylamine::CHEMBL92818

SMILES N[C@H](COCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1

InChI Key InChIKey=UYZIPLMTFSGKAJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069648   

TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069648((S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl...)
Affinity DataIC50: 13nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069648((S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl...)
Affinity DataIC50: 13nMAssay Description:Binding affinity to human Tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM50069648((S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl...)
Affinity DataIC50: 580nMAssay Description:Inhibition of binding to L-type [Ca2+] channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article