BDBM50069643 5-{[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethylamino]-methyl}-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL358437

SMILES FC(F)(F)c1cc(COC[C@@H](NCc2n[nH]c(=O)[nH]2)c2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=STQPZMKBIAWKGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069643   

TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069643(5-{[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-ph...)
Affinity DataIC50: 2.40nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed