BDBM50069598 (2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-{2-(4-chloro-phenyl)-2-[(E)-hydroxyimino]-ethylsulfanylmethyl}-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL326148

SMILES CC(C)C[C@H]([C@H](CSCC(N=O)c1ccc(Cl)cc1)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=NDALNAHQTWQQRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50069598   

TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069598((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-{2...)
Affinity DataIC50: 60nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069598((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-{2...)
Affinity DataIC50: 34nMAssay Description:Inhibitory activity towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed