BDBM50069573 3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5-ylmethyl-5-propoxy-1H-indole-2-carboxylic acid::CHEMBL69150

SMILES CCCOc1ccc2n(Cc3ccc4nsnc4c3)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1

InChI Key InChIKey=LQKHSTBTPGBUTB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069573   

TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50069573(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)
Affinity DataIC50: 97nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50069573(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50069573(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)
Affinity DataIC50: 97nMAssay Description:Potency at Endothelin A receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed