BDBM50069559 Biphalin Analogue::CHEMBL2371057

SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)NNC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=GLZFVTVMXOQFMT-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069559   

TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50069559(Biphalin Analogue | CHEMBL2371057)
Affinity DataIC50: 1.70nMAssay Description:Compound was tested for binding affinity towards mu opioid receptor in guinea pig brain homogenates using [3H]CTOP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50069559(Biphalin Analogue | CHEMBL2371057)
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration required against biological activity of mu opioid receptor from guinea pig ileum (GPI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50069559(Biphalin Analogue | CHEMBL2371057)
Affinity DataKi:  0.790nMAssay Description:Compound was tested for binding affinity towards mu opioid receptor in guinea pig brain homogenates using [3H]CTOP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50069559(Biphalin Analogue | CHEMBL2371057)
Affinity DataKi:  6.40nMAssay Description:Compound was tested for binding affinity towards Opioid receptor delta 1 in guinea pig brain homogenates using [3H][p-Cl-Phe]-DPDPE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed