BDBM50069282 4-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-benzamide::CHEMBL346973

SMILES CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(N)cc1OC

InChI Key InChIKey=ATMCNNNBGDVDQH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069282   

TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069282(4-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan...)
Affinity DataIC50: 127nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069282(4-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan...)
Affinity DataIC50: 8.5nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069282(4-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan...)
Affinity DataIC50: 127nMAssay Description:Inhibition of the binding of radioligand [3H]spiperone to dopamine receptor D2 in rat brain synaptic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069282(4-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan...)
Affinity DataIC50: 8.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed