BDBM50069242 (6aR,10aS)-4-Methoxy-7,9-dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-fg]quinoline::CHEMBL435240

SMILES COn1cc2C[C@@H]3[C@@H](C=C(C)CN3C)c3cccc1c23

InChI Key InChIKey=OZXRMPYHEDZXHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50069242   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50069242((6aR,10aS)-4-Methoxy-7,9-dimethyl-4,6,6a,7,8,10a-h...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of p56 lck autophosphorylation, gamma-[33P]ATP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50069242((6aR,10aS)-4-Methoxy-7,9-dimethyl-4,6,6a,7,8,10a-h...)
Affinity DataIC50: 2.85E+5nMAssay Description:Inhibition of p72 syk autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed