BDBM50069239 4-[2-(6-{[Bis-(4-methoxy-phenyl)-methyl]-carbamoyl}-benzofuran-2-yl)-phenoxy]-butyric acid::CHEMBL155094

SMILES COc1ccc(cc1)C(NC(=O)c1ccc2cc(oc2c1)-c1ccccc1OCCCC(O)=O)c1ccc(OC)cc1

InChI Key InChIKey=YWWSOZJTTVIDTJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069239   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069239(4-[2-(6-{[Bis-(4-methoxy-phenyl)-methyl]-carbamoyl...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 1 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069239(4-[2-(6-{[Bis-(4-methoxy-phenyl)-methyl]-carbamoyl...)
Affinity DataIC50: 930nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 2 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50069239(4-[2-(6-{[Bis-(4-methoxy-phenyl)-methyl]-carbamoyl...)
Affinity DataIC50: 36nMAssay Description:In vitro inhibitory activity against rat testosterone 5 alpha reductase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed