BDBM50069237 4-{2-[6-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-phenoxy}-butyric acid::CHEMBL152401

SMILES OC(=O)CCCOc1ccccc1-c1cc2ccc(cc2o1)C(=O)NC(c1ccccc1)c1ccccc1

InChI Key InChIKey=YUEWUJHHFXPSJH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069237   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069237(4-{2-[6-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-ph...)
Affinity DataIC50: 270nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 2 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069237(4-{2-[6-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-ph...)
Affinity DataIC50: 62nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 1 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50069237(4-{2-[6-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-ph...)
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory activity against rat testosterone 5 alpha reductase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed