BDBM50069235 4-[2-(6-{[Bis-(4-fluoro-phenyl)-methyl]-carbamoyl}-benzofuran-2-yl)-phenoxy]-butyric acid::CHEMBL153258

SMILES OC(=O)CCCOc1ccccc1-c1cc2ccc(cc2o1)C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=JUSOMMXOAWTGPZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069235   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069235(4-[2-(6-{[Bis-(4-fluoro-phenyl)-methyl]-carbamoyl}...)
Affinity DataIC50: 340nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 2 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069235(4-[2-(6-{[Bis-(4-fluoro-phenyl)-methyl]-carbamoyl}...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 1 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50069235(4-[2-(6-{[Bis-(4-fluoro-phenyl)-methyl]-carbamoyl}...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibitory activity against rat testosterone 5 alpha reductase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed