BDBM50069104 CHEMBL1449583::US9182402, 4

SMILES Cc1cccc(c1)C1Nc2cccc3cccc(N1)c23

InChI Key InChIKey=HPFJVSRZYNTHHT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069104   

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50: 350nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50: 1.96E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50: 350nMAssay Description:Inhibition of hepsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed