BDBM50069072 (R)-2,3,3,8-Tetramethyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one::CHEMBL351519

SMILES C[C@H]1Nc2cc3n(C)c(=O)cc(c3cc2C1(C)C)C(F)(F)F

InChI Key InChIKey=WHJQDVRYEXYKBA-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069072   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069072((R)-2,3,3,8-Tetramethyl-5-trifluoromethyl-1,2,3,8-...)
Affinity DataKi:  9nMAssay Description:Binding affinity against Androgen receptor transfected into COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069072((R)-2,3,3,8-Tetramethyl-5-trifluoromethyl-1,2,3,8-...)
Affinity DataIC50: 22nMAssay Description:Antagonistic activity (IC50) against human androgen receptor (hAR) in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069072((R)-2,3,3,8-Tetramethyl-5-trifluoromethyl-1,2,3,8-...)
Affinity DataEC50:  380nMAssay Description:Agonistic activity (EC50) against human androgen receptor (hAR) in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed