BDBM50069069 (5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one::CHEMBL163425

SMILES Cn1c2cc3N[C@@H]4CCCC[C@@H]4c3cc2c(cc1=O)C(F)(F)F

InChI Key InChIKey=YXFRGFFRCABTFT-UHFFFAOYSA-N

Data  1 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50069069   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069069((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...)
Affinity DataKi:  4nMAssay Description:Binding affinity against Androgen receptor transfected into COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069069((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...)
Affinity DataEC50:  10nMAssay Description:Agonistic activity (EC50) against human androgen receptor (hAR) in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069069((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...)
Affinity DataIC50: 150nMAssay Description:Antagonistic activity against hPR in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069069((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...)
Affinity DataIC50: 2.90E+3nMAssay Description:Antagonistic activity against hMR in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069069((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonistic activity against Glucocorticoid receptor in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069069((5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against Estrogen receptor in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed