BDBM50069067 (5bR,7S,9aR)-1,7-Dimethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one::CHEMBL165803

SMILES C[C@H]1CC[C@H]2Nc3cc4n(C)c(=O)cc(c4cc3[C@H]2C1)C(F)(F)F

InChI Key InChIKey=APDOEOQZQMSOFL-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50069067   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069067((5bR,7S,9aR)-1,7-Dimethyl-4-trifluoromethyl-1,5b,6...)
Affinity DataIC50: 48nMAssay Description:Antagonistic activity (IC50) against human androgen receptor (hAR) in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069067((5bR,7S,9aR)-1,7-Dimethyl-4-trifluoromethyl-1,5b,6...)
Affinity DataKi:  94nMAssay Description:Binding affinity against Androgen receptor transfected into COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069067((5bR,7S,9aR)-1,7-Dimethyl-4-trifluoromethyl-1,5b,6...)
Affinity DataIC50: 380nMAssay Description:Antagonistic activity against hPR in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069067((5bR,7S,9aR)-1,7-Dimethyl-4-trifluoromethyl-1,5b,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against hMR in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069067((5bR,7S,9aR)-1,7-Dimethyl-4-trifluoromethyl-1,5b,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against Estrogen receptor in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069067((5bR,7S,9aR)-1,7-Dimethyl-4-trifluoromethyl-1,5b,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against Glucocorticoid receptor in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed