BDBM50069059 (5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one::CHEMBL423620

SMILES C[C@]12CCCC(C)(C)[C@H]1Nc1cc3[nH]c(=O)cc(c3cc21)C(F)(F)F

InChI Key InChIKey=CMHJMUZTXMDMKL-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50069059   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069059((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...)
Affinity DataIC50: 51nMAssay Description:Antagonistic activity (IC50) against human androgen receptor (hAR) in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069059((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...)
Affinity DataKi:  77nMAssay Description:Binding affinity against Androgen receptor transfected into COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069059((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...)
Affinity DataIC50: 430nMAssay Description:Antagonistic activity against hPR in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069059((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...)
Affinity DataIC50: 570nMAssay Description:Antagonistic activity against hMR in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069059((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonistic activity against Glucocorticoid receptor in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069059((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against Estrogen receptor in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed