BDBM50069048 (7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine::CHEMBL159903

SMILES Fc1ccc(OC[C@@H]2CC[C@H]3CN(CCN3C2)c2ncccn2)cc1

InChI Key InChIKey=UHFPHCOQBXQSQQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50069048   

TargetD(4) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50069048((7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-pyrimidin-2-...)
Affinity DataKi:  2.80nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50069048((7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-pyrimidin-2-...)
Affinity DataKi:  1.20E+3nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed