BDBM50068823 1-(3-{[2,6-Dimethyl-5-methylcarbamoyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3-carbonyl]-amino}-propyl)-4-phenyl-piperidine-4-carboxylic acid ethyl ester::CHEMBL355910

SMILES CCOC(=O)C1(CCN(CCCNC(=O)C2=C(C)N=C(C)C(C2c2ccc(cc2)[N+]([O-])=O)C(=O)NC)CC1)c1ccccc1

InChI Key InChIKey=KJPZGJYUDUIYGW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50068823   

TargetAlpha-1A adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068823(1-(3-{[2,6-Dimethyl-5-methylcarbamoyl-4-(4-nitro-p...)
Affinity DataKi:  6.12nMAssay Description:Binding affinity was determined for the alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068823(1-(3-{[2,6-Dimethyl-5-methylcarbamoyl-4-(4-nitro-p...)
Affinity DataKi:  6.20nMAssay Description:Binding affinity to Homo sapiens (human) alpha1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetAlpha-1B adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068823(1-(3-{[2,6-Dimethyl-5-methylcarbamoyl-4-(4-nitro-p...)
Affinity DataKi:  3.92E+3nMAssay Description:Binding affinity was determined for the alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068823(1-(3-{[2,6-Dimethyl-5-methylcarbamoyl-4-(4-nitro-p...)
Affinity DataKi:  5.60E+3nMAssay Description:Binding affinity was determined for the alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed