BDBM50068725 2-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL80506

SMILES Cc1noc(NS(=O)(=O)c2ccccc2Br)c1C

InChI Key InChIKey=FICDMFJBLNFMAR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068725   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068725(2-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulf...)
Affinity DataIC50: 620nMAssay Description:Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068725(2-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulf...)
Affinity DataKi:  8.00E+3nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle (Endothelin A receptor) was determined by rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed