BDBM50068351 CHEMBL3402317

SMILES COc1ccc2cc(ccc2c1)C(C)c1nc2s\c(=C/C(/C)=C/c3ccccc3)c(=O)n2n1

InChI Key InChIKey=FTQZTYNKJVJGGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068351   

TargetProstaglandin G/H synthase 1(Sheep)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068351(CHEMBL3402317)
Affinity DataIC50: 6.47E+4nMAssay Description:Inhibition of ovine recombinant COX-1 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068351(CHEMBL3402317)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of human recombinant COX-2 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed