BDBM50068236 CHEMBL1576791

SMILES Oc1c(Sc2cccc3cccnc23)cc(NS(=O)(=O)c2ccccc2)c2ccccc12

InChI Key InChIKey=PQIKPRFFZWZBIW-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50068236   

TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50068236(CHEMBL1576791)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50068236(CHEMBL1576791)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068236(CHEMBL1576791)
Affinity DataKi:  1.56E+4nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6R expressed in HEK293 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068236(CHEMBL1576791)
Affinity DataKi:  2.37E+4nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5-HT1A receptor expressed in HEK293 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068236(CHEMBL1576791)
Affinity DataKi:  2.54E+4nMAssay Description:Displacement of [3H]-5-CT from human cloned 5-HT7R expressed in HEK293 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068236(CHEMBL1576791)
Affinity DataKi:  3.42E+4nMAssay Description:Displacement of [3H]-ketanserin from human cloned 5-HT2A receptor expressed in CHO-K1 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed