BDBM50068234 5'-Chloro-1H,1''H-[3,3':3',3''-terindol]-2'(1'H)-one (4c)::CHEMBL2011865

SMILES Clc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12

InChI Key InChIKey=KQTQQJVFFASAJD-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50068234   

TargetAlpha-glucosidase MAL32(Baker's yeast)
Jishou University

LigandPNGBDBM50068234(CHEMBL2011865 | 5'-Chloro-1H,1''H-[3,3...)
Affinity DataIC50: 5.05E+4nMpH: 6.8 T: 2°CAssay Description:The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2017
Entry Details

TargetProbable maltase-glucoamylase 2(Human)
Babasaheb Bhimrao Ambedkar University (A Central University)

Curated by ChEMBL
LigandPNGBDBM50068234(CHEMBL2011865 | 5'-Chloro-1H,1''H-[3,3...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl-alpha-d-glucopyranoside as substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068234(CHEMBL2011865 | 5'-Chloro-1H,1''H-[3,3...)
Affinity DataKi:  670nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6R expressed in HEK293 cells using seven compounds concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068234(CHEMBL2011865 | 5'-Chloro-1H,1''H-[3,3...)
Affinity DataKi:  720nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6R expressed in HEK293 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068234(CHEMBL2011865 | 5'-Chloro-1H,1''H-[3,3...)
Affinity DataKi:  2.45E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5-HT1A receptor expressed in HEK293 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068234(CHEMBL2011865 | 5'-Chloro-1H,1''H-[3,3...)
Affinity DataKi:  1.58E+4nMAssay Description:Displacement of [3H]-ketanserin from human cloned 5-HT2A receptor expressed in CHO-K1 cells using seven compounds concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068234(CHEMBL2011865 | 5'-Chloro-1H,1''H-[3,3...)
Affinity DataKi:  1.81E+4nMAssay Description:Displacement of [3H]-5-CT from human cloned 5-HT7R expressed in HEK293 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50068234(CHEMBL2011865 | 5'-Chloro-1H,1''H-[3,3...)
Affinity DataKi:  1.83E+4nMAssay Description:Displacement of [3H]-ketanserin from human cloned 5-HT2A receptor expressed in CHO-K1 cells at 0.1 and 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed