BDBM50068224 (E)-1,3-Bis-(4-hydroxy-phenyl)-propenone::1,3-bis(4-hydroxyphenyl)prop-2-en-1-one::4',4-Dihydroxychalcone::4,4'-dihydroxychalcone::CHEMBL145927

SMILES Oc1ccc(\C=C\C(=O)c2ccc(O)cc2)cc1

InChI Key InChIKey=FZQLEXXZAVVCCA-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50068224   

TargetPolyphenol oxidase 2(White button mushroom)
Department of Functional Crop

Curated by ChEMBL
LigandPNGBDBM50068224((E)-1,3-Bis-(4-hydroxy-phenyl)-propenone | 4,4'-di...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50068224((E)-1,3-Bis-(4-hydroxy-phenyl)-propenone | 4,4'-di...)
Affinity DataIC50: 1.17E+5nMAssay Description:Inhibition of bovine milk xanthine oxidase pre-incubated for 30 mins followed by xanthine addition and measured every 30 secs for 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetTissue factor(Human)TBA
LigandPNGBDBM50068224((E)-1,3-Bis-(4-hydroxy-phenyl)-propenone | 4,4'-di...)
Affinity DataIC50: 0.960nMAssay Description:Inhibition of tissue factor in Homo sapiens (human) THP1-cells using factor 10a chromogenic substrate assessed as inhibition of LPS-iduced procoagula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetPolyphenol oxidase 2(White button mushroom)
Department of Functional Crop

Curated by ChEMBL
LigandPNGBDBM50068224((E)-1,3-Bis-(4-hydroxy-phenyl)-propenone | 4,4'-di...)
Affinity DataKi:  2.90E+3nMAssay Description:Competitive inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed