BDBM50068001 CHEMBL3400817

SMILES c1cc2c(nc1CNC34CCC(CC3)(OC4)C[C@@]5(CN6c7c5c(cnc7C=CC6=O)F)O)NC(=O)CO2

InChI Key InChIKey=XTHQMKOHGLBSON-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50068001   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50068001(CHEMBL3400817)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human ERG by MK499 binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50068001(CHEMBL3400817)
Affinity DataIC50: 1.74E+5nMAssay Description:Inhibition of human ERG expressed in CHO cells by Patch express assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50068001(CHEMBL3400817)
Affinity DataIC50: 1.74E+5nMAssay Description:Inhibition of human ERG expressed in CHO cells measured over 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50068001(CHEMBL3400817)
Affinity DataIC50: 6.00E+4nMAssay Description:Displacement of MK499 from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50068001(CHEMBL3400817)
Affinity DataIC50: 1.74E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed