BDBM50067917 (E)-N-{1-[3-(2-Methyl-quinolin-8-yloxymethyl)-2,4-bis-(2-oxo-pyrrolidin-1-yl)-phenyl]-1H-pyrrol-2-ylmethyl}-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide; hydrochloride::CHEMBL553315

SMILES Cc1ccc2cccc(OCc3c(ccc(c3N3CCCC3=O)-n3cccc3CNC(=O)\C=C\c3ccc(cc3)N3CCCC3=O)N3CCCC3=O)c2n1

InChI Key InChIKey=KLMFGRRYSNJMFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067917   

TargetB2 bradykinin receptor(Guinea pig)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067917((E)-N-{1-[3-(2-Methyl-quinolin-8-yloxymethyl)-2,4-...)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of the specific binding of [3H]BK to Bradykinin receptor B2 in guinea pig ileum membrane preparationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067917((E)-N-{1-[3-(2-Methyl-quinolin-8-yloxymethyl)-2,4-...)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of the specific binding of [3H]BK to human recombinant Bradykinin receptor B2 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed