BDBM50067563 (S)-2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphenyl-2-carbonyl]-amino}-4-methylsulfanyl-butyric acid::2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphenyl-2-carbonyl]-amino}-4-methylsulfanyl-butyric acid::CHEMBL274122

SMILES CSCC[C@H](NC(=O)c1ccc(COc2cccnc2)cc1-c1ccccc1C)C(O)=O

InChI Key InChIKey=OKLOPBKXGZVBCB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50067563   

LigandPNGBDBM50067563((S)-2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphen...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibitory activity was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067563((S)-2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphen...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against farnesyltransferase (FT) using SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067563((S)-2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphen...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase purified from bovine brain using scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067563((S)-2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphen...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against yeast farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50067563((S)-2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphen...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of farnesyltransferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50067563((S)-2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphen...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant FTase using [3H]farnesyldiphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed