BDBM50067504 CHEMBL3398246

SMILES FC(F)(F)C(=O)Nc1cc(cc2SSSSSc12)C(F)(F)F

InChI Key InChIKey=OMMBYCFXYYODAV-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50067504   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50067504(CHEMBL3398246)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) assessed as increase in fluorescenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50067504(CHEMBL3398246)
Affinity DataIC50: 24nMAssay Description:Inhibition of STEP (unknown origin) pre-incubated for 10 mins before addition of p-nitrophenyl phosphate substrate in absence of GSHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50067504(CHEMBL3398246)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of STEP (unknown origin) pre-incubated for 10 mins before addition of p-nitrophenyl phosphate substrate in presence of 1 mM GSHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50067504(CHEMBL3398246)
Affinity DataKi:  235nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed