BDBM50067500 5-Methoxycanthinone

SMILES COc1cc2nccc3c4ccccc4n(c23)c1=O

InChI Key InChIKey=TXEFUSAHPIYZHD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067500   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Toho University

Curated by ChEMBL
LigandPNGBDBM50067500(5-Methoxycanthinone)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Toho University

Curated by ChEMBL
LigandPNGBDBM50067500(5-Methoxycanthinone)
Affinity DataKi:  1.03E+4nMAssay Description:Non-competitive inhibition of PTP1B (unknown origin) assessed as hydrolysis of para-nitrophenylphosphate by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed