BDBM50067488 2-(4-Amino-phenyl)-3-[(benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid ethyl ester::CHEMBL435974

SMILES CCOC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(N)cc1

InChI Key InChIKey=KOJMOHDUQCENEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067488   

TargetGonadotropin-releasing hormone receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50067488(2-(4-Amino-phenyl)-3-[(benzyl-methyl-amino)-methyl...)
Affinity DataIC50: 4nMAssay Description:The Compound was tested for the concentration to inhibit 50% of [125 I ]leuprorelin binding to the cloned human Leutinizing releasing hormone recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50067488(2-(4-Amino-phenyl)-3-[(benzyl-methyl-amino)-methyl...)
Affinity DataIC50: 500nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor in the membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed