BDBM50067484 3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-methoxy-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid ethyl ester::CHEMBL135103::ethyl 3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-2-(4-methoxyphenyl)-4-oxothieno[2,3b]pyridine-5-carboxylate

SMILES CCOC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(OC)cc1

InChI Key InChIKey=LQIABJAVEVBDFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50067484   

TargetGonadotropin-releasing hormone receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50067484(ethyl 3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difl...)
Affinity DataIC50: 6nMAssay Description:The Compound was tested for the concentration to inhibit 50% of [125 I ]leuprorelin binding to the cloned human Leutinizing releasing hormone recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50067484(ethyl 3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difl...)
Affinity DataIC50: 800nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor in the membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50067484(ethyl 3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difl...)
Affinity DataIC50: 6nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed