BDBM50067482 6-[(2-Methoxy-benzyl)-methyl-amino]-hexanoic acid [8-({6-[(2-methoxy-benzyl)-methyl-amino]-hexanoyl}-methyl-amino)-octyl]-methyl-amide::CAPROCTAMINE::CHEMBL11805::CHEMBL222856::CHEMBL557586::N,N''-(octane-1,8-diyl)bis(6-((2-methoxybenzyl)(methyl)amino)-N-methylhexanamide)

SMILES COc1ccccc1CN(C)CCCCCC(=O)N(C)CCCCCCCCN(C)C(=O)CCCCCN(C)Cc1ccccc1OC

InChI Key InChIKey=HDAQKLAKMZNBQB-UHFFFAOYSA-N

Data  4 KI  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50067482   

TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity on Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against acetylcholinesterase in human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetCholinesterase(Human)
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibitory activity against butyrylcholinesterase (BChE) in human erythrocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetCholinesterase(Human)
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of human recombinant butyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of Butyrylcholinesterase (BChE) of human erythrocytes [-log IC50 (uM)]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 104nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of acetylcholinesterase (AChE) of human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataKi:  0.100nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataKi:  104nMAssay Description:Competitive inhibition constant for AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataKi:  104nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataKi:  104nMAssay Description:Inhibitory activity of compound against acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed