BDBM50067447 3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol::CHEMBL334898

SMILES C[C@H]1C2CCCC1(CCN2CCc1ccccc1)c1cccc(O)c1

InChI Key InChIKey=FJRARMQVERMSNJ-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50067447   

TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  0.340nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding in guinea pig caudate stimulated by DAMGO (Opioid receptor mu 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding in guinea pig caudate stimulated by U69,593 in Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  3.10nMAssay Description:Binding activity against Opioid receptor mu 1 using [3H]DAMGO as radioligand in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  13nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding in guinea pig caudate stimulated by SNC80 (Opioid receptor delta 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  15nMAssay Description:Binding activity against kOpioid receptor kappa 1 using [3H]U-69593 as radioligand in guinea pig membranes. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  270nMAssay Description:Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  272nMAssay Description:Binding activity against Opioid receptor delta 1 using [3H]DADLE as radioligand in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed