BDBM50067446 3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol::CHEMBL133815

SMILES C[C@H]1C2CCCC1(CCN2C)c1cccc(O)c1

InChI Key InChIKey=JBSRPCWYMOJXAM-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50067446   

TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067446(3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...)
Affinity DataKi:  21nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding in guinea pig caudate stimulated by DAMGO (Opioid receptor mu 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067446(3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...)
Affinity DataKi:  105nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding in guinea pig caudate stimulated by U69,593 in Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067446(3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...)
Affinity DataKi:  166nMAssay Description:Binding activity against Opioid receptor mu 1 using [3H]DAMGO as radioligand in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067446(3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...)
Affinity DataKi:  750nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding in guinea pig caudate stimulated by SNC80 (Opioid receptor delta 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067446(3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...)
Affinity DataKi:  816nMAssay Description:Binding activity against Opioid receptor kappa 1 using [3H]U-69593 as radioligand in guinea pig membranes. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067446(3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding activity against Opioid receptor delta 1 using [3H]DADLE as radioligand in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed